Do eukaryotic cells have restriction endonucleases?

Question:

Do eukaryotic cells have restriction endonucleases? Justify your answer.

Solution:

No, eukaryotic cells do not have restriction endonucleases. This is because the DNA of eukaryotes is highly methylated by a modification enzyme, called methylase. Methylation protects the DNA from the activity of restriction enzymes .These enzymes are present in prokaryotic cells where they help prevent the invasion of DNA by virus.

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